טכנולוגים ציטוגנטיים

CARO E J GIBSON (אין סיכוי) 15 days ago

Cancer cytogenetics sees that 90% of first event abnormal chromosome events are balanced with the remaining 10% of those unbalanced. Nothing can do that 90% of early diagnosis but the human eye and if we wait long enough and allow other chromosome events to occur, those may be unbalanced. It is ONLY the unbalanced changes that can be picked up by microarray (but the actual abnormal percentage needs to be higher than 15% over the normal clone cell line populations) and sequencing. So, if you want a early diagnosis that all of our treatments are geared towards, it's the HUMAN EYE on band for band analyses of Geisma stained chromosomes. A sea of normal cells, go find the 2 or 3 with a balanced translocation between 2 or more chromosomes is ONE EVENT.

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Caro (אין סיכוי) 1 month ago

Low level percentage abnormal chromosome event in a sea of normal metaphase spreads. Most 90% are balanced rearrangements making early diagnosis not detectable by DNA sequencing nor FISH nor microarray. G banded metaphase spreads is the gold standard of cancer cytogenetics using bone marrow taps.

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